Sunday, September 23, 2018

Hidradenitis suppurativa extensive


We are used to seeing hidradenitis suppurativa involving the axillae and groins but sometimes it becomes more extensive and sinuses and draining abscesses form extensively on the trunk as in this case. Hidradenitis suppurativa is considered a disease of apocrine glands usually affecting young people or obese diabetics. Bacterial cultures can sometimes be negative but always ask for anaerobic culture as well. Patients with this condition may have other inflammatory diseases  such as cystic acne and dissecting cellulitis of the scalp. Treatment with antibiotics and surgical drainage of abscesses was often unsuccessful and long term scarring and depression were commonly seen in these patients. A major recent development has been the availability on the PBS of the biologic adalimumab, a cytokine TNF alpha inhibitor given by subcutaneous injection every two weeks. This shuts off the inflammation in this disease and the abscesses and sinuses dry up. Therapy has to be continued in the longer term but patients get their life back!